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DDX3 DEAD-Box RNA Helicase Is a Host Factor That Restricts Hepatitis B Virus Replication at the Transcriptional Level

DDX3 is a member of the DEAD-box RNA helicase family, involved in mRNA metabolism, including transcription, splicing, and translation. We previously identified DDX3 as a hepatitis B virus (HBV) polymerase (Pol) binding protein, and by using a transient transfection, we found that DDX3 inhibits HBV r...

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Foilsithe in:J Virol
Main Authors: Ko, Chunkyu, Lee, Sooyoung, Windisch, Marc P., Ryu, Wang-Shick
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2014
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248967/
https://ncbi.nlm.nih.gov/pubmed/25231298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02035-14
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