Activation of Peripheral Blood Mononuclear Cells by Dengue Virus Infection Depotentiates Balapiravir

In a recent clinical trial, balapiravir, a prodrug of a cytidine analog (R1479), failed to achieve efficacy (reducing viremia after treatment) in dengue patients, although the plasma trough concentration of R1479 remained above the 50% effective concentration (EC(50)). Here, we report experimental e...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chen, Yen-Liang, Abdul Ghafar, Nahdiyah, Karuna, Ratna, Fu, Yilong, Lim, Siew Pheng, Schul, Wouter, Gu, Feng, Herve, Maxime, Yokohama, Fumiaki, Wang, Gang, Cerny, Daniela, Fink, Katja, Blasco, Francesca, Shi, Pei-Yong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2014
Gaiak:
Vaccines and Antiviral Agents
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911617/
https://ncbi.nlm.nih.gov/pubmed/24257621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02841-13
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak