A Randomized, Double-Blind Placebo Controlled Trial of Balapiravir, a Polymerase Inhibitor, in Adult Dengue Patients

Background. Dengue is the most common arboviral infection of humans. There are currently no specific treatments for dengue. Balapiravir is a prodrug of a nucleoside analogue (called R1479) and an inhibitor of hepatitis C virus replication in vivo. Methods. We conducted in vitro experiments to determ...

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Main Authors: Nguyen, Nguyet Minh, Tran, Chau Nguyen Bich, Phung, Lam Khanh, Duong, Kien Thi Hue, Huynh, Huy le Anh, Farrar, Jeremy, Nguyen, Quyen Than Ha, Tran, Hien Tinh, Nguyen, Chau Van Vinh, Merson, Laura, Hoang, Long Truong, Hibberd, Martin L., Aw, Pauline P. K., Wilm, Andreas, Nagarajan, Niranjan, Nguyen, Dung Thi, Pham, Mai Phuong, Nguyen, Truong Thanh, Javanbakht, Hassan, Klumpp, Klaus, Hammond, Janet, Petric, Rosemary, Wolbers, Marcel, Nguyen, Chinh Tran, Simmons, Cameron P.
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2013
נושאים:
Major Articles and Brief Reports
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610419/
https://ncbi.nlm.nih.gov/pubmed/22807519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis470
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