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H3 Stalk-Based Chimeric Hemagglutinin Influenza Virus Constructs Protect Mice from H7N9 Challenge

The recent outbreak of H7N9 influenza virus infections in humans in China has raised concerns about the pandemic potential of this strain. Here, we test the efficacy of H3 stalk-based chimeric hemagglutinin universal influenza virus vaccine constructs to protect against H7N9 challenge in mice. Chime...

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Main Authors: Krammer, Florian, Margine, Irina, Hai, Rong, Flood, Alexander, Hirsh, Ariana, Tsvetnitsky, Vadim, Chen, Dexiang, Palese, Peter
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911549/
https://ncbi.nlm.nih.gov/pubmed/24307585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03183-13
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