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Utility of Humanized BLT Mice for Analysis of Dengue Virus Infection and Antiviral Drug Testing

Dengue virus (DENV) is the cause of a potentially life-threatening disease that affects millions of people worldwide. The lack of a small animal model that mimics the symptoms of DENV infection in humans has slowed the understanding of viral pathogenesis and the development of therapies and vaccines...

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Autors principals: Frias-Staheli, Natalia, Dorner, Marcus, Marukian, Svetlana, Billerbeck, Eva, Labitt, Rachael N., Rice, Charles M., Ploss, Alexander
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911540/
https://ncbi.nlm.nih.gov/pubmed/24335303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03085-13
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