Development of human CD4(+)FoxP3(+) regulatory T cells in human stem cell factor–, granulocyte-macrophage colony-stimulating factor–, and interleukin-3–expressing NOD-SCID IL2Rγ(null) humanized mice

Human hematolymphoid mice have become valuable tools for the study of human hematopoiesis and uniquely human pathogens in vivo. Recent improvements in xenorecipient strains allow for long-term reconstitution with a human immune system. However, certain hematopoietic lineages, for example, the myeloi...

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Hlavní autoři: Billerbeck, Eva, Barry, Walter T., Mu, Kathy, Dorner, Marcus, Rice, Charles M., Ploss, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2011
Témata:
Hematopoiesis and Stem Cells
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062310/
https://ncbi.nlm.nih.gov/pubmed/21252091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-08-301507
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