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Characterization of human antiviral adaptive immune responses during hepatotropic virus infection in HLA-transgenic human immune system mice

Humanized mice have emerged as a promising model to study human immunity in vivo. While they are susceptible to many pathogens exhibiting an almost exclusive human tropism, human immune responses to infection remain functionally impaired. It has recently been demonstrated that the expression of HLA...

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Detalhes bibliográficos
Main Authors: Billerbeck, Eva, Horwitz, Joshua A., Labitt, Rachael N., Donovan, Bridget M., Vega, Kevin, Budell, William C., Koo, Gloria C., Rice, Charles M., Ploss, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735836/
https://ncbi.nlm.nih.gov/pubmed/23833235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201518
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