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Characterization of human antiviral adaptive immune responses during hepatotropic virus infection in HLA-transgenic human immune system mice
Humanized mice have emerged as a promising model to study human immunity in vivo. While they are susceptible to many pathogens exhibiting an almost exclusive human tropism, human immune responses to infection remain functionally impaired. It has recently been demonstrated that the expression of HLA...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3735836/ https://ncbi.nlm.nih.gov/pubmed/23833235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201518 |
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