An Antibody Blocking Activin Type II Receptors Induces Strong Skeletal Muscle Hypertrophy and Protects from Atrophy

The myostatin/activin type II receptor (ActRII) pathway has been identified to be critical in regulating skeletal muscle size. Several other ligands, including GDF11 and the activins, signal through this pathway, suggesting that the ActRII receptors are major regulatory nodes in the regulation of mu...

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Bibliografiske detaljer
Main Authors: Lach-Trifilieff, Estelle, Minetti, Giulia C., Sheppard, KellyAnn, Ibebunjo, Chikwendu, Feige, Jerome N., Hartmann, Steffen, Brachat, Sophie, Rivet, Helene, Koelbing, Claudia, Morvan, Frederic, Hatakeyama, Shinji, Glass, David J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911487/
https://ncbi.nlm.nih.gov/pubmed/24298022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01307-13
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