Autocrine activin A signalling in ovarian cancer cells regulates secretion of interleukin 6, autophagy, and cachexia

BACKGROUND: The majority of patients with advanced cancer develop cachexia, a weight loss syndrome that severely reduces quality of life and limits survival. Our understanding of the underlying mechanisms that cause the condition is limited, and there are currently no treatment options that can comp...

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Detalhes bibliográficos
Publicado no:J Cachexia Sarcopenia Muscle
Main Authors: Pettersen, Kristine, Andersen, Sonja, van der Veen, Anna, Nonstad, Unni, Hatakeyama, Shinji, Lambert, Christian, Lach‐Trifilieff, Estelle, Moestue, Siver, Kim, Jana, Grønberg, Bjørn Henning, Schilb, Alain, Jacobi, Carsten, Bjørkøy, Geir
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7015233/
https://ncbi.nlm.nih.gov/pubmed/31436048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12489
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