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Distinct Roles of Candida albicans Drug Resistance Transcription Factors TAC1, MRR1, and UPC2 in Virulence

Azoles are widely used in antifungal therapy in medicine. Resistance to azoles can occur in Candida albicans principally by overexpression of multidrug transporter gene CDR1, CDR2, or MDR1 or by overexpression of ERG11, which encodes the azole target. The expression of these genes is controlled by t...

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Hlavní autoři: Lohberger, Andrea, Coste, Alix T., Sanglard, Dominique
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910953/
https://ncbi.nlm.nih.gov/pubmed/24243794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00245-13
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