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Examining the virulence of Candida albicans transcription factor mutants using Galleria mellonella and mouse infection models

The aim of the present study was to identify Candida albicans transcription factors (TFs) involved in virulence. Although mice are considered the gold-standard model to study fungal virulence, mini-host infection models have been increasingly used. Here, barcoded TF mutants were first screened in mi...

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Bibliografiske detaljer
Udgivet i:Front Microbiol
Main Authors: Amorim-Vaz, Sara, Delarze, Eric, Ischer, Françoise, Sanglard, Dominique, Coste, Alix T
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4419840/
https://ncbi.nlm.nih.gov/pubmed/25999923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2015.00367
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