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Examining the virulence of Candida albicans transcription factor mutants using Galleria mellonella and mouse infection models

The aim of the present study was to identify Candida albicans transcription factors (TFs) involved in virulence. Although mice are considered the gold-standard model to study fungal virulence, mini-host infection models have been increasingly used. Here, barcoded TF mutants were first screened in mi...

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Bibliografske podrobnosti
izdano v:Front Microbiol
Main Authors: Amorim-Vaz, Sara, Delarze, Eric, Ischer, Françoise, Sanglard, Dominique, Coste, Alix T
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4419840/
https://ncbi.nlm.nih.gov/pubmed/25999923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2015.00367
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