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The Transcription Factor Ndt80 Does Not Contribute to Mrr1-, Tac1-, and Upc2-Mediated Fluconazole Resistance in Candida albicans

The pathogenic yeast Candida albicans can develop resistance to the widely used antifungal agent fluconazole, which inhibits ergosterol biosynthesis, by the overexpression of genes encoding multidrug efflux pumps or ergosterol biosynthesis enzymes. Zinc cluster transcription factors play a central r...

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Hlavní autoři: Sasse, Christoph, Schillig, Rebecca, Dierolf, Franziska, Weyler, Michael, Schneider, Sabrina, Mogavero, Selene, Rogers, P. David, Morschhäuser, Joachim
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181345/
https://ncbi.nlm.nih.gov/pubmed/21980509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025623
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