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Proteomic Analysis of Mrr1p- and Tac1p-Associated Differential Protein Expression in Azole-Resistant Clinical Isolates of Candida albicans

Azole resistance in Candida albicans is frequently caused by the overexpression of multi-drug efflux pump genes MDR1, CDR1, and CDR2 due to gain-of-function mutations in the zinc cluster transcription factors Mrr1p and Tac1p. In this study, we performed a comparative proteomic analysis to identify p...

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發表在:Proteomics Clin Appl
Main Authors: Hoehamer, Christopher F., Cummings, Edwin D., Hilliard, George M., Morschhäuser, Joachim, Rogers, P. David
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694560/
https://ncbi.nlm.nih.gov/pubmed/21136999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prca.200800252
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