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Proteomic Analysis of Mrr1p- and Tac1p-Associated Differential Protein Expression in Azole-Resistant Clinical Isolates of Candida albicans
Azole resistance in Candida albicans is frequently caused by the overexpression of multi-drug efflux pump genes MDR1, CDR1, and CDR2 due to gain-of-function mutations in the zinc cluster transcription factors Mrr1p and Tac1p. In this study, we performed a comparative proteomic analysis to identify p...
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| Publicado en: | Proteomics Clin Appl |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4694560/ https://ncbi.nlm.nih.gov/pubmed/21136999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prca.200800252 |
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