TGF-β-activated Smad3 represses MEF2-dependent transcription in myogenic differentiation

Transforming growth factor β (TGF-β) inhibits myogenesis and associated gene expression. We previously reported that the TGF-β signaling effector Smad3 mediates this inhibition, by interfering with the assembly of myogenic bHLH transcription factor heterodimers on E-box sequences in the regulatory r...

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Pubblicato in:	EMBO J
Autori principali:	Liu, Dong, Kang, Jong Seok, Derynck, Rik
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2004
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391082/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15044954/ https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600179
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