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TGF-β-activated Smad3 represses MEF2-dependent transcription in myogenic differentiation
Transforming growth factor β (TGF-β) inhibits myogenesis and associated gene expression. We previously reported that the TGF-β signaling effector Smad3 mediates this inhibition, by interfering with the assembly of myogenic bHLH transcription factor heterodimers on E-box sequences in the regulatory r...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC391082/ https://ncbi.nlm.nih.gov/pubmed/15044954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600179 |
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