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Thymocyte apoptosis drives the intrathymic generation of regulatory T cells
Maintenance of immune tolerance critically depends upon regulatory T cells that express the transcription factor forkhead box P3 (Foxp3). These CD4(+) T cells can be generated in the thymus, termed thymus-derived regulatory T cells (tTregs), but their developmental pathway remains incompletely under...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3910656/ https://ncbi.nlm.nih.gov/pubmed/24474796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320319111 |
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