Loading...
Activation-induced cell death of self-reactive regulatory T cells drives autoimmunity
Activation of self-reactive T cells is a major driver to autoimmunity and is suppressed by mechanisms of regulation. In a humanized model of autoimmune thyroiditis, we investigated the mechanism underlying break of tolerance. Here, we found that a human TCR specific for the self-antigen thyroid pero...
Na minha lista:
| Udgivet i: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2019
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6936679/ https://ncbi.nlm.nih.gov/pubmed/31818938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1910281116 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|