Deletion of conserved protein phosphatases reverses defects associated with mitochondrial DNA damage in Saccharomyces cerevisiae

Mitochondrial biogenesis is regulated by signaling pathways sensitive to extracellular conditions and to the internal environment of the cell. Therefore, treatments for disease caused by mutation of mtDNA may emerge from studies of how signal transduction pathways command mitochondrial function. We...

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Bibliographic Details
Main Authors: Garipler, Görkem, Mutlu, Nebibe, Lack, Nathan A., Dunn, Cory D.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2014
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910629/
https://ncbi.nlm.nih.gov/pubmed/24474773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312399111
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