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Deletion of conserved protein phosphatases reverses defects associated with mitochondrial DNA damage in Saccharomyces cerevisiae

Mitochondrial biogenesis is regulated by signaling pathways sensitive to extracellular conditions and to the internal environment of the cell. Therefore, treatments for disease caused by mutation of mtDNA may emerge from studies of how signal transduction pathways command mitochondrial function. We...

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Autors principals: Garipler, Görkem, Mutlu, Nebibe, Lack, Nathan A., Dunn, Cory D.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910629/
https://ncbi.nlm.nih.gov/pubmed/24474773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312399111
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