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Searching for missing heritability: Designing rare variant association studies
Genetic studies have revealed thousands of loci predisposing to hundreds of human diseases and traits, revealing important biological pathways and defining novel therapeutic hypotheses. However, the genes discovered to date typically explain less than half of the apparent heritability. Because effor...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2014
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3910587/ https://ncbi.nlm.nih.gov/pubmed/24443550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322563111 |
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