SQSTM1 is a Pathogenic Target of 5q Copy Number Gains in Kidney Cancer

Clear cell renal cell carcinoma (ccRCC) is the most common form of kidney cancer and is often linked to loss of chromosome 3p, which harbors the VHL tumor suppressor gene, loss of chromosome 14q, which includes HIF1A, and gain of chromosome 5q. The relevant target(s) on chromosome 5q is not known. H...

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Autori principali: Li, Lianjie, Shen, Chuan, Nakamura, Eijiro, Ando, Kiyohiro, Signoretti, Sabina, Beroukhim, Rameen, Cowley, Glenn S., Lizotte, Patrick, Liberzon, Ella, Bair, Steven, Root, David E., Tamayo, Pablo, Tsherniak, Aviad, Cheng, Su-Chun, Tabak, Barbara, Jacobsen, Anders, Hakimi, A. Ari, Schultz, Nikolaus, Ciriello, Giovanni, Sander, Chris, Hsieh, James J., Kaelin, William G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910168/
https://ncbi.nlm.nih.gov/pubmed/24332042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2013.10.025
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