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Mutation of Pro-258 in transmembrane domain 6 constitutively activates the G protein-coupled alpha-factor receptor.

The alpha-factor pheromone receptor stimulates MATa yeast cells to undergo conjugation. The receptor contains seven transmembrane domains that function in ligand binding and in transducing a signal to the cytoplasmic receptor sequences to mediate G protein activation. A genetic screen was used to is...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Konopka, J B, Margarit, S M, Dube, P
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1996
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC39101/
https://ncbi.nlm.nih.gov/pubmed/8692892
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