Dominant-Negative Mutations in the G-Protein-Coupled α-Factor Receptor Map to the Extracellular Ends of the Transmembrane Segments

G-protein-coupled receptors (GPCRs) transduce the signals for a wide range of hormonal and sensory stimuli by activating a heterotrimeric guanine nucleotide-binding protein (G protein). The analysis of loss-of-function and constitutively active receptor mutants has helped to reveal the functional pr...

Full description

Saved in:
Bibliographic Details
Main Authors: Dosil, Mercedes, Giot, Loïc, Davis, Colleen, Konopka, James B.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC109184/
https://ncbi.nlm.nih.gov/pubmed/9742115
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items