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Dominant-Negative Mutations in the G-Protein-Coupled α-Factor Receptor Map to the Extracellular Ends of the Transmembrane Segments

G-protein-coupled receptors (GPCRs) transduce the signals for a wide range of hormonal and sensory stimuli by activating a heterotrimeric guanine nucleotide-binding protein (G protein). The analysis of loss-of-function and constitutively active receptor mutants has helped to reveal the functional pr...

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Publicat a:Mol Cell Biol
Autors principals: Dosil, Mercedes, Giot, Loïc, Davis, Colleen, Konopka, James B.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109184/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9742115/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.10.5981
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