Five-transmembrane domains appear sufficient for a G protein-coupled receptor: Functional five-transmembrane domain chemokine receptors

The putative seven-transmembrane (TM) domains have been the structural hallmark for the superfamily of heterotrimeric G protein-coupled receptors (GPCRs) that regulate a variety of cellular functions by mediating a large number of extracellular signals. Five-TM GPCR mutants of chemokine receptor CCR...

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Detalhes bibliográficos
Main Authors: Ling, Kun, Wang, Ping, Zhao, Jian, Wu, Ya-Lan, Cheng, Zhi-Jie, Wu, Guo-Xiang, Hu, Wei, Ma, Lan, Pei, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC22163/
https://ncbi.nlm.nih.gov/pubmed/10393923
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