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Five-transmembrane domains appear sufficient for a G protein-coupled receptor: Functional five-transmembrane domain chemokine receptors

The putative seven-transmembrane (TM) domains have been the structural hallmark for the superfamily of heterotrimeric G protein-coupled receptors (GPCRs) that regulate a variety of cellular functions by mediating a large number of extracellular signals. Five-TM GPCR mutants of chemokine receptor CCR...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Ling, Kun, Wang, Ping, Zhao, Jian, Wu, Ya-Lan, Cheng, Zhi-Jie, Wu, Guo-Xiang, Hu, Wei, Ma, Lan, Pei, Gang
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1999
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22163/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10393923/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.14.7922
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