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Molecular Insights into the Transmembrane Domain of the Thyrotropin Receptor.

The thyrotropin receptor (TSHR) is a G protein-coupled receptor (GPCR) that is member of the leucine-rich repeat subfamily (LGR). In the absence of crystal structure, the success of rational design of ligands targeting the receptor internal cavity depends on the quality of the TSHR models built. In...

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Autors principals: Vanessa Chantreau, Bruck Taddese, Mathilde Munier, Louis Gourdin, Daniel Henrion, Patrice Rodien, Marie Chabbert
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2015-01-01
Col·lecció:PLoS ONE
Accés en línia:https://doi.org/10.1371/journal.pone.0142250
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