Five-transmembrane domains appear sufficient for a G protein-coupled receptor: Functional five-transmembrane domain chemokine receptors

The putative seven-transmembrane (TM) domains have been the structural hallmark for the superfamily of heterotrimeric G protein-coupled receptors (GPCRs) that regulate a variety of cellular functions by mediating a large number of extracellular signals. Five-TM GPCR mutants of chemokine receptor CCR...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Ling, Kun, Wang, Ping, Zhao, Jian, Wu, Ya-Lan, Cheng, Zhi-Jie, Wu, Guo-Xiang, Hu, Wei, Ma, Lan, Pei, Gang
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1999
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22163/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10393923/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.14.7922
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