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The lacI shuttle: rapid analysis of the mutagenic specificity of ultraviolet light in human cells.

A system has been devised that allows the effect of mutagens acting in human cells to be readily analyzed at the DNA sequence level. The bacterial gene lacI, carried on a shuttle vector, is introduced into human tissue culture cells by transfection and allowed to replicate in the cell nucleus. Twent...

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Detalhes bibliográficos
Main Authors: Lebkowski, J S, Clancy, S, Miller, J H, Calos, M P
Formato: Artigo
Idioma:Inglês
Publicado em: 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC390966/
https://ncbi.nlm.nih.gov/pubmed/3001711
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