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Structure-guided approach to site-specific fluorophore labeling of the lac repressor LacI

The lactose operon repressor protein LacI has long served as a paradigm of the bacterial transcription factors. However, the mechanisms whereby LacI rapidly locates its cognate binding site on the bacterial chromosome are still elusive. Single-molecule fluorescence imaging approaches are well suited...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kipper, Kalle, Eremina, Nadja, Marklund, Emil, Tubasum, Sumera, Mao, Guanzhong, Lehmann, Laura Christina, Elf, Johan, Deindl, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983854/
https://ncbi.nlm.nih.gov/pubmed/29856839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198416
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