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Structure-guided approach to site-specific fluorophore labeling of the lac repressor LacI
The lactose operon repressor protein LacI has long served as a paradigm of the bacterial transcription factors. However, the mechanisms whereby LacI rapidly locates its cognate binding site on the bacterial chromosome are still elusive. Single-molecule fluorescence imaging approaches are well suited...
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Publicado no: | PLoS One |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5983854/ https://ncbi.nlm.nih.gov/pubmed/29856839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198416 |
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