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Mutagenesis in the lacI gene target of E. coli: improved analysis for lacI(d) and lacO mutants

The lacI gene of E. coli has been a highly useful target for studies of mutagenesis, particularly for analysis of the specificity (spectrum) of mutations generated under a variety of conditions and in various genetic backgrounds. The gene encodes the repressor of the lac operon, and lacI-defective m...

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Autori principali: Swerdlow, Sarah J., Schaaper, Roel M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217168/
https://ncbi.nlm.nih.gov/pubmed/25771873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2014.09.004
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