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Antibody Discovery Ex Vivo Accelerated by the LacO/LacI Regulatory Network

Monoclonal antibodies (mAbs) can be potent and highly specific therapeutics, diagnostics and research reagents. Nonetheless, mAb discovery using current in vivo or in vitro approaches can be costly and time-consuming, with no guarantee of success. We have established a platform for rapid discovery a...

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Detalhes bibliográficos
Main Authors: Yabuki, Munehisa, Cummings, W. Jason, Leppard, John B., Immormino, Robert M., Wood, Christi L., Allison, Daniel S., Gray, Patrick W., Tjoelker, Larry W., Maizels, Nancy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338700/
https://ncbi.nlm.nih.gov/pubmed/22558313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036032
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