Spectra of spontaneous and mutagen-induced mutations in the lacI gene in transgenic mice.

Transgenic mice with a lambda shuttle vector containing a lacI target gene were generated for use as a short-term, in vivo mutagenesis assay. The gene is recovered from the treated mice by exposing mouse genomic DNA to in vitro packaging extracts and plating the rescued phage on agar plates containi...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Kohler, S W, Provost, G S, Fieck, A, Kretz, P L, Bullock, W O, Sorge, J A, Putman, D L, Short, J M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52424/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1832771/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.18.7958
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