Spectra of spontaneous and mutagen-induced mutations in the lacI gene in transgenic mice.

Transgenic mice with a lambda shuttle vector containing a lacI target gene were generated for use as a short-term, in vivo mutagenesis assay. The gene is recovered from the treated mice by exposing mouse genomic DNA to in vitro packaging extracts and plating the rescued phage on agar plates containi...

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Bibliographische Detailangaben
Hauptverfasser: Kohler, S W, Provost, G S, Fieck, A, Kretz, P L, Bullock, W O, Sorge, J A, Putman, D L, Short, J M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1991
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC52424/
https://ncbi.nlm.nih.gov/pubmed/1832771
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