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Through a glass, darkly: reflections of mutation from lacI transgenic mice.

The study of mutational frequency (Mf) and specificity in aging Big Blue lacI transgenic mice provides a unique opportunity to determine mutation rates (MR) in vivo in different tissues. We found that MR are not static, but rather, vary with the age or developmental stage of the tissue. Although Mf...

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Detalhes bibliográficos
Main Authors: Stuart, G R, Glickman, B W
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1461138/
https://ncbi.nlm.nih.gov/pubmed/10880494
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