Llwytho...

Insights into the Motif Preference of APOBEC3 Enzymes

We used a multivariate data analysis approach to identify motifs associated with HIV hypermutation by different APOBEC3 enzymes. The analysis showed that APOBEC3G targets G mainly within GG, TG, TGG, GGG, TGGG and also GGGT. The G nucleotides flanked by a C at the 3′ end (in +1 and +2 positions) wer...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ebrahimi, Diako, Alinejad-Rokny, Hamid, Davenport, Miles P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909203/
https://ncbi.nlm.nih.gov/pubmed/24498164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087679
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!