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APOBEC3 Has Not Left an Evolutionary Footprint on the HIV-1 Genome

It is known that the human immune proteins APOBEC3G and -F (hA3G/F) can inhibit Vif-deficient HIV by G-to-A mutation; however, the roles of these enzymes in the evolution of HIV are debated. We argue that if evolutionary pressure from hA3G/F exists there should be evidence of their imprint on the HI...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ebrahimi, Diako, Anwar, Firoz, Davenport, Miles P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165787/
https://ncbi.nlm.nih.gov/pubmed/21697498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00658-11
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