Cardiac GRK2 Ablation Induces a Novel Ca(2+) Handling Phenotype Resistant to Adverse Alterations and Remodeling After Myocardial Infarction

BACKGROUND: G-protein coupled receptor kinase 2 (GRK2) is a primary regulator of β-adrenergic signaling in the heart. GRK2 ablation ameliorates heart failure development but the cellular mechanisms have not been elucidated and are the aim of this study. METHODS AND RESULTS: Myocyte contractility, Ca...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Raake, Philip W., Zhang, Xiaoying, Vinge, Leif E., Brinks, Henriette, Gao, Erhe, Jaleel, Naser, Li, Yingxin, Tang, Mingxin, Most, Patrick, Dorn, Gerald W., Houser, Steven R., Katus, Hugo A., Chen, Xiongwen, Koch, Walter J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908785/
https://ncbi.nlm.nih.gov/pubmed/22496128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.111.044255
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia