The effect of STAT3 Inhibition on status epilepticus and subsequent spontaneous seizures in the Pilocarpine Model of Acquired Epilepsy

Pilocarpine-induced status epilepticus (SE), which results in temporal lobe epilepsy (TLE) in rodents, activates the JAK/STAT pathway. In the current study, we evaluate whether brief exposure to a selective inhibitor of the JAK/STAT pathway (WP1066) early after the onset of SE effects the severity o...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Grabenstatter, H. L., Angel, Y. Cruz Del, Carlsen, J., Wempe, M. F., White, A. M., Cogswell, M., Russek, S. J., Brooks-Kayal, A. R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908775/
https://ncbi.nlm.nih.gov/pubmed/24051278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.09.003
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