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Suppressing CRE transcription shortens status epilepticus and decreases the number of spontaneous seizures in the pilocarpine model of epilepsy

OBJECTIVE: Current epilepsy therapies directed at altering the function of neurotransmitter receptors, ion channels or release of synaptic vesicles fails to prevent seizures in approximately thirty percent of patients. A better understanding of the molecular mechanism underlying epilepsy is needed t...

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Detalhes bibliográficos
Publicado no:Epilepsia
Main Authors: Zhu, Xinjian, Dubey, Deepti, Bermudez, Camilo, Porter, Brenda E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689408/
https://ncbi.nlm.nih.gov/pubmed/26419901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.13211
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