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The effect of STAT3 Inhibition on status epilepticus and subsequent spontaneous seizures in the Pilocarpine Model of Acquired Epilepsy
Pilocarpine-induced status epilepticus (SE), which results in temporal lobe epilepsy (TLE) in rodents, activates the JAK/STAT pathway. In the current study, we evaluate whether brief exposure to a selective inhibitor of the JAK/STAT pathway (WP1066) early after the onset of SE effects the severity o...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3908775/ https://ncbi.nlm.nih.gov/pubmed/24051278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.09.003 |
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