Comparative Molecular Field Analysis of fenoterol derivatives interacting with an agonist-stabilized form of the β(2)-adrenergic receptor

The β(2)-adrenergic receptor (β(2)-AR) agonist [(3)H]-(R,R′)-methoxyfenoterol was employed as the marker ligand in displacement studies measuring the binding affinities (K(i) values) of the stereoisomers of a series of 4′-methoxyfenoterol analogs in which the length of the alkyl substituent at α′ po...

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Hauptverfasser: Plazinska, Anita, Pajak, Karolina, Rutkowska, Ewelina, Jimenez, Lucita, Kozocas, Joseph, Koolpe, Gary, Tanga, Mary, Toll, Lawrence, Wainer, Irving W., Jozwiak, Krzysztof
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908673/
https://ncbi.nlm.nih.gov/pubmed/24326276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.11.030
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