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The effect of fenoterol stereochemistry on the β2 adrenergic receptor system: ligand directed chiral recognition
The β(2) adrenergic receptor (β(2)-AR) is a model system for studying the ligand recognition process in G-protein coupled receptors. Fenoterol (FEN) is a β(2)-AR selective agonist that has two centers of chirality and exists as four stereoisomers. Radioligand binding studies determined that stereoch...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3164500/ https://ncbi.nlm.nih.gov/pubmed/21618615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chir.20963 |
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