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The effect of fenoterol stereochemistry on the β2 adrenergic receptor system: ligand directed chiral recognition

The β(2) adrenergic receptor (β(2)-AR) is a model system for studying the ligand recognition process in G-protein coupled receptors. Fenoterol (FEN) is a β(2)-AR selective agonist that has two centers of chirality and exists as four stereoisomers. Radioligand binding studies determined that stereoch...

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Detaylı Bibliyografya
Asıl Yazarlar: Jozwiak, Krzysztof, Plazinska, Anita, Toll, Lawrence, Jimenez, Lucita, Woo, Anthony Yiu-Ho, Xiao, Rui-Ping, Wainer, Irving W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164500/
https://ncbi.nlm.nih.gov/pubmed/21618615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chir.20963
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