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Oncogenic K-ras promotes early carcinogenesis in the mouse proximal colon
Oncogenic K-ras mutations are frequently observed in colon cancers and contribute to transformed growth. Oncogenic K-ras is detected in aberrant crypt foci (ACF), precancerous colonic lesions, demonstrating that acquisition of a K-ras mutation is an early event in colon carcinogenesis. Here, we inve...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3908548/ https://ncbi.nlm.nih.gov/pubmed/18271008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.23383 |
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