Protein kinase Cι is required for Ras transformation and colon carcinogenesis in vivo

Protein kinase C ι (PKCι) has been implicated in Ras signaling, however, a role for PKCι in oncogenic Ras-mediated transformation has not been established. Here, we show that PKCι is a critical downstream effector of oncogenic Ras in the colonic epithelium. Transgenic mice expressing constitutively...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Murray, Nicole R., Jamieson, Lee, Yu, Wangsheng, Zhang, Jie, Gökmen-Polar, Yesim, Sier, Deborah, Anastasiadis, Panos, Gatalica, Zoran, Thompson, E. Aubrey, Fields, Alan P.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2004
Matèries:
Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172278/
https://ncbi.nlm.nih.gov/pubmed/15024028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200311011
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars