Protein kinase Cι is required for Ras transformation and colon carcinogenesis in vivo

Protein kinase C ι (PKCι) has been implicated in Ras signaling, however, a role for PKCι in oncogenic Ras-mediated transformation has not been established. Here, we show that PKCι is a critical downstream effector of oncogenic Ras in the colonic epithelium. Transgenic mice expressing constitutively...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Murray, Nicole R., Jamieson, Lee, Yu, Wangsheng, Zhang, Jie, Gökmen-Polar, Yesim, Sier, Deborah, Anastasiadis, Panos, Gatalica, Zoran, Thompson, E. Aubrey, Fields, Alan P.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2004
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172278/
https://ncbi.nlm.nih.gov/pubmed/15024028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200311011
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker