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Variegated transgene expression in mouse mammary gland is determined by the transgene integration locus.

Mice carrying an ovine beta-lactoglobulin (BLG) transgene secrete BLG protein into their milk. To explore transgene expression stability, we studied expression levels in three BLG transgenic mouse lines. Unexpectedly, two lines exhibited variable levels of transgene expression. Copy number within li...

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Hlavní autoři: Dobie, K W, Lee, M, Fantes, J A, Graham, E, Clark, A J, Springbett, A, Lathe, R, McClenaghan, M
Médium: Artigo
Jazyk:Inglês
Vydáno: 1996
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC39082/
https://ncbi.nlm.nih.gov/pubmed/8692874
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