Variegated transgene expression in mouse mammary gland is determined by the transgene integration locus.

Mice carrying an ovine beta-lactoglobulin (BLG) transgene secrete BLG protein into their milk. To explore transgene expression stability, we studied expression levels in three BLG transgenic mouse lines. Unexpectedly, two lines exhibited variable levels of transgene expression. Copy number within li...

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Bibliografiske detaljer
Main Authors: Dobie, K W, Lee, M, Fantes, J A, Graham, E, Clark, A J, Springbett, A, Lathe, R, McClenaghan, M
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC39082/
https://ncbi.nlm.nih.gov/pubmed/8692874
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