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Aberrantly spliced HTT, a new player in Huntington’s disease pathogenesis
Huntington’s disease (HD) is an adult-onset neurodegenerative disorder caused by a mutated CAG repeat in the huntingtin gene that is translated into an expanded polyglutamine tract. The clinical manifestation of HD is a progressive physical, cognitive, and psychiatric deterioration that is eventuall...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Landes Bioscience
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3907474/ https://ncbi.nlm.nih.gov/pubmed/24256709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.26706 |
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