The Covalent Trimethoprim Chemical Tag Facilitates Single Molecule Imaging with Organic Fluorophores

Chemical tags can be used to selectively label proteins with fluorophores that have high photon outputs. By permitting straightforward single molecule (SM) detection and imaging with organic fluorophores, chemical tags have the potential to advance SM imaging as a routine experimental tool for study...

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Bibliografske podrobnosti
Main Authors: Wang, Tracy Y., Friedman, Larry J., Gelles, Jeff, Min, Wei, Hoskins, Aaron A., Cornish, Virginia W.
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2014
Teme:
Proteins and Nucleic Acids
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907213/
https://ncbi.nlm.nih.gov/pubmed/24411259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.11.4488
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