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Functional Relationships between Agonist Binding Sites and Coupling Regions of Homomeric Cys-Loop Receptors

Each subunit in a homopentameric Cys-loop receptor contains a specialized coupling region positioned between the agonist binding domain and the ion conductive channel. To determine the contribution of each coupling region to the stability of the open channel, we constructed a receptor subunit (α7-5-...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Andersen, Natalia, Corradi, Jeremías, Bartos, Mariana, Sine, Steven M., Bouzat, Cecilia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907114/
https://ncbi.nlm.nih.gov/pubmed/21389221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5940-10.2011
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